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梦境增强

梦境增强是一种提高睡眠梦境状态的主观强度、生动性和频率的效应。它最常见于中度剂量的促梦化合物的作用下,这是一类在睡前服用以专门增强梦境的致幻剂。

梦境增强是一种增强睡眠中梦境状态的主观强度、生动度和频率的效果。12 这种效果还会使梦具有更复杂、更连贯的情节,以及更高水平的细节和清晰度。2 此外,该效果会大大提高梦变为清醒梦的可能性。

梦境增强最常见于中度剂量的促梦化合物的作用下,这是一类在睡前服用以专门增强梦境的致幻剂。3 不过,它也可能作为残留副作用出现,即在种类极其繁多的物质的作用下入睡时发生。在其他情况下,它也可能作为一种相对持续的效应出现,是致幻剂持续性感知障碍(HPPD)的一种症状。

分析

已有数百项研究将胆碱能药物局部或全身应用于脑桥内侧网状结构,以诱导并增强REM睡眠的产生。4 一些胆碱能药物可诱导REM睡眠,另一些则可增强REM睡眠。25678 然而,关于这种效应是否仅限于患有抑郁的人群,现有证据相互矛盾。78910 胺能类药物,如血清素和/或去甲肾上腺素再摄取抑制类抗抑郁药,会抑制REM睡眠。21112 非抗抑郁药,包括苯丙胺类、巴比妥类和阿片类麻醉药物,未显示出大幅且持续的REM睡眠减少及随后的反弹。13

参考文献

参见

外部链接

  1. 梦(维基百科)
  2. Oneirogen(维基百科)
  3. 药物与梦(PDF)

引用

  1. Pavel, S., Goldstein, R., & Petrescu, M. (1980). Vasotocin, melatonin and narcolepsy: possible involvement of the pineal gland in its patho-physiological mechanism. Peptides, 1(4), 281-284.
  2. Pace‐Schott, E. F., Gersh, T., Silvestri, R., Stickgold, R., Salzman, C., & Hobson, J. A. (2001). SSRI treatment suppresses dream recall frequency but increases subjective dream intensity in normal subjects. Journal of Sleep Research, 10(2), 129-142.
  3. Oneirogens
  4. Kubin, L. (2001). Carbachol models of REM sleep: recent developments and new directions. Archives italiennes de biologie, 139(1), 147-168.
  5. BERGER, M., & RIEMANN, D. (1993). REM sleep in depression—an overview. Journal of Sleep Research, 2(4), 211-223.
  6. Sitaram, N., Moore, A. M., & Gillin, J. C. (1978). Experimental acceleration and slowing of REM sleep ultradian rhythm by cholinergic agonist and antagonist. Nature, 274(5670), 490.
  7. Sitaram, N., Moore, A. M., & Gillin, J. C. (1978). The effect of physostigmine on normal human sleep and dreaming. Archives of general psychiatry, 35(10), 1239-1243.
  8. Sitaram, N., Wyatt, R. J., Dawson, S., & Gillin, J. C. (1976). REM sleep induction by physostigmine infusion during sleep. Science, 191(4233), 1281-1283.
  9. Berger, M., Riemann, D., Höchli, D., & Spiegel, R. (1989). The cholinergic rapid eye movement sleep induction test with RS-86: State or trait marker of depression?. Archives of General Psychiatry, 46(5), 421-428.
  10. Lauriello, J., Kenny, W. M., Sutton, L., Golshan, S., Ruiz, C., Kelsoe, J., ... & Gillin, J. C. (1993). The cholinergic REM sleep induction test with pilocarpine in mildly depressed patients and normal controls. Biological psychiatry, 33(1), 33-39.
贡献者:Josie·Kaylee·Graham·Natalie